Supersensitivity and gastric emptying after vagotomy.
نویسندگان
چکیده
Investigations were carried out in man and dog to study the validity of Cannon's law of denervation supersensitivity in relation to parasympathetic denervation of the stomach. Subthreshold doses of carbachol did not accelerate gastric emptying before vagotomy but caused a significant increase in the rate of gastric emptying after vagotomy. These findings may be relevant to aberrations of gastrointestinal motility after vagotomy and may provide the basis of a test for completeness of gastric vagotomy.
منابع مشابه
Alimentary transit and supersensitivity after vagotomy in the rat.
The effect of a subthreshold dose of carbachol on alimentary transit of a radioisotopically labelled fluid test meal was measured before and after vagotomy and pyloromyotomy in rats. Vagotomy itself had a transient slowing effect on the rates of gastric emptying and transit in the upper small intestine. Subthreshold carbachol had no effect before vagotomy but accelerated gastric emptying and sm...
متن کاملThe effect of preserving antral innervation and of a pyloroplasty on gastric emptying after vagotomy in man.
A prospective randomized trial of 40 duodenal ulcer patients is reviewed. The patients had one of four operations (selective vagotomy, proximal gastric vagotomy, selective vagotomy plus pyloroplasty, or proximal gastric vagotomy plus pyloroplasty). The gastric emptying of a hypertonic fluid meal was assessed before and three to four months after operation. Selective vagotomy without a drainage ...
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Little is known of the temporal and quantitative relationships between emptying of the stomach and of the gall bladder in patients with duodenal ulcer before and after vagotomy. A non-invasive double isotope technique was used to investigate these relationships in 27 patients with a duodenal ulcer, before and after operation-truncal vagotomy and pyloroplasty (TV + P; n = 15) and highly selectiv...
متن کاملGastric emptying in control subjects and patients with duodenal ulcer before and after vagotomy.
The emptying of a solid meal labelled with Indium 113mDTPA from the stomach was studied with a gamma camera in 26 normal subjects, 27 patients with duodenal ulcer, on 41 occasions after truncal vagotomy and pyloroplasty and 38 times after highly selective vagotomy. Applying the method of principal component analysis to the results, differences were detected between control and duodenal ulcer su...
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ورودعنوان ژورنال:
- Gut
دوره 11 6 شماره
صفحات -
تاریخ انتشار 1970